Biosketch:

2000, B.Eng., Zhejiang University
2005, Ph.D., Zhejiang University
2005-2008, Postdoc & Visiting scientist, US Food and Drug Administration

Research Interests:

Research in his group includes both computational and experimental approaches to advancing regulatory science of Chinese Medicine, emphasizing a 'systems-level' perspective. Some areas of special interest include 1) network pharmacology, 2) systems toxicology.

Selected publications:

1. Zhenhao Li, Shun Xiao, Ni Ai, Kedi Luo, Xiaohui Fan*, Yiyu Cheng. Derivative multiple reaction monitoring and single herb calibration approach for multiple components quantification of Traditional Chinese Medicine analogous formulae. Journal of Chromatography A, 2015, 1376:126–142.

2. Ni Ai, Xiaohui Fan*, Sean Ekins*. In silico methods for predicting drug-drug interactions with cytochrome P-450s, transporters and beyond. Advanced Drug Delivery Reviews. 2015, doi:10.1016/j.addr.2015.03.006.

3. Yecheng Jin, Qian Chen, Xiang Li, Xiaohui Fan*, Zheng Li*. Astragali Radix protects myocardium from ischemia injury by modulating energy metabolism.International Journal of Cardiology, 2014. 176: 1312–1315.

4. Xiaohui Fan, Edward K. Lobenhofer, Minjun Chen, et. al. Consistency of predictive signature genes and classifiers generated using different microarray platforms. Pharmacogenomics Journal. 2010. 10(4): 247-257. (Highlighted by Pharmacogenomics)

5. Xiaohui Fan, Leming Shi, Hong Fang, Yiyu Cheng, Roger Perkins, Weida Tong*. DNA microarrays are predictive of cancer prognosis: A re-evaluation. Clinical Cancer Research. 2010, 16(2):629-636.

Grants & Research Sponsors:

1. National Natural Science Foundation of China (81373893), 2014.1-2017.12, PI

2. National Natural Science Foundation of China (81173465), 2012.1-2015.12, PI

3. National S&T Major Projects - Key New Drug Innovation (2012ZX09505001-001), 2012.1-2015.12, Co-PI

4. National Natural Science Foundation of China(30801556), 2009.1-2011.12, PI

5. National S&T Major Projects - Key New Drug Innovation (2008ZX09202-006), 2008.10-2010.12, PI

Conference & invited talks:

1. Shanghai International conference on Traditional Chinese Medicine and natural medicine, Hangzhou, China. 2010.

2. FDA-China International Forum and Workshop, Shanghai, China. 2009

3. The Joint Symposium of 5^th ICT and TIES-2009. Seoul, Korea. 2009.

4. BioEco 2009, Tianjin, China. 2009.

5. Westlake International Conference on Personalized Medicine, Hangzhou China. 2009.