EDUCATION:

2008        Ph.D. in Pharmaceutical analysis, specialized in drug transport and metabolism

ZhejiangUniversity, Hangzhou, China

1998        M.S. in Pharmaceutics

ZhejiangMedical University, Hangzhou, China

1992        B.S. magna cum laude in Pharmaceutical

ZhejiangMedical University, Hangzhou, China

EXPERIENCE:

2010.12~        Professor, Zhejiang University

2009.11~2010.5   Visiting Scientist, National University of Singapore

1998.9-present    Lectuer, Associate Professor, Zhejiang University

1992.8-1998.8    Assistant, Zhejiang Medical University, Hangzhou, China

RESEARCH INTERESTS

Biomaterials, Controlled and targeted drug delivery, Cancer therapy, gene delivery, nanotechnology, Advanced Formulation Design, Enhancing Dissolution Rates and Bioavailability of drugs, Pharmacokinetic studies of drugs.

PUBLICATIONS:          

1.Hong Yuan*, Linjuan Lu, Yong-Zhong Du, Fu-Qiang Hu, Stearic Acid-g-chitosan Polymeric Micelle for Oral Drug Delivery: In Vitro Transport and in Vivo Absorption. Molecular Pharmaceutics, 2011, 8（1）225-238

2.Hong Yuan*, Wei Zhang, Yong-Zhong Du, Fu-Qiang Hu, Ternary nanoparticles of anionic lipid nanoparticles/protamine/DNA for gene delivery. International Journal Pharmaceutics, 2010, 392, 224-231.

3.Fu-Qiang Hu, Li-Na Liu, Yong-Zhong Du, Hong Yuan*. Synthesis and antitumor activity of doxorubicin conjugated stearicacid-g-chitosan oligosaccharide polymeric micelles. Biomaterials, 2009, 30, 6955-6963

4.Hong Yuan, Sai-Ping Jiang, Yong-Zhong Du, Jing Miao, Xing-Guo Zhang, Fu-Qiang Hu, Strategic approaches for improving lipid nanoparticles entrapping hydrophilic peptide drugs. Colloids and Surfaces B: Biointerfaces. 2009, 70, 248-253.

5.Fu-Qiang Hu, Xiu-ling Wu, Yong-Zhong Du, Jian You, Hong Yuan*, Cellular uptake and cytotoxicity of shell crosslinked stearic acid-grafted chitosan oligosaccharide micelles encapsulating doxorubicin. European Journal of Pharmaceutics and Biopharmaceutics, 2008, 69, 117–125

6.Fu-Qiang Hu, Yu Zhang, Yong-Zhong Du, Hong Yuan*, Nimodipine loaded lipid nanospheres prepared by solvent diffusion method in a drug saturated aqueous system. International Journal Pharmaceutics, 2008, 348, 146-152.

7.Hong Yuan*, Ling-Fei Huang, Yong-Zhong Du, Xiao-Ying Ying, Jian You, Fu-Qiang Hu, Su Zeng, Solid lipid nanoparticles prepared by solvent diffusion method in a nanoreactor system. Colloids and Surfaces B: Biointerfaces. 2008, 61, 132-137.

8.Hong Yuan, Jing Miao, Yong-Zhong Du, Jian You, Fu-Qiang Hu*, Su Zeng, Cellular uptake of solid lipid nanoparticles and cytotoxicity of encapsulated paclitaxel in A549 cancer cells. International Journal Pharmaceutics, 2008, 348, 137-145.

9.Hong Yuan*, Lei-Lei Wang, Yong-Zhong Du, Jian You, Fu-Qiang Hu, Su Zeng, Preparation and characteristics of nanostructured lipid carriers for control-releasing progesterone by melt-emulsification. Colloids and Surfaces B: Biointerfaces. 2007, 60(2), 174-179.

10.  Hong Yuan*, Jian Chen, Yong-Zhong Du, Fu-Qiang Hu, Su Zeng, Studies on oral absorption of stearic acid SLN by a novel fluorometric method. Colloids and Surfaces B: Biointerfaces. 2007, 58, 157-164.

PROJECTS:

1. Basic studies on the efficiencies of poorly water-soluble drugs improved by nano technology.

  National Basic Research Program of China (973 Program), 2009, 2009CB930305

2. studies on design of nucleal targeting cattier and antitumor pharmacodynamics.

National Nature Science Foundation of China, 2007, 30672552

3. The research of the lymphocyte-targeting drug delivery technique and development of new drugs.

Hi-tech Research and Development Program of China, 2004, 2004AA2Z3040